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Sibutramine Disease Interactions Side Effects Interactions Pregnancy More Breastfeeding Warnings User Reviews Support Group Q & A Drug Interactions

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Buy Sibutramine online without prescription , formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries.Buy sibutramine online without prescription

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Uses Of Sibutramine:

  • Psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or pre-existing mania
  • Patients with a history of or a predisposition to drug or alcohol abuse
  • Hypersensitivity to the drug or any of the inactive ingredients
  • Patients below 18 and above 65 years of age
  • History of peripheral arterial disease
  • Hypertension that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension
  • Existing pulmonary hypertension
  • Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction
  • A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial
  • occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack (TIA))
  • Stroke or transient ischemic attack (TIA)
  • Hyperthyroidism (overactive thyroid gland)
  • Closed-angle glaucoma
  • Seizure disorders
  • Enlargement of the prostate gland with urinary retention (relative contraindication)
  • Pheochromocytoma
  • Pregnant and lactating women (relative contraindication). online.

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The aim of the study was to assess the effectiveness and safety of long-term sibutramine therapy in routine clinical practice. Methods: In total, 98,774 patients (82.3% women, 17.7% men) from 142 cities of the Russian Federation were enrolled in the PRIMAVERA program. The mean age of the patients was 39.39 ± 10.38 years, the mean body weight was 99.1 ± 14.28 kg, and the mean BMI was 35.7 ± 4.41 kg/m2. The duration of the sibutramine therapy was determined by physicians: 59.3% of patients took the drug for 6 months, the treatment course of 37.7% of patients was 12 months, and 3% of patients had treatment for 3 months. Results: The BMI reduction correlated with the treatment duration: 3.4 ± 1.53 kg/m2 after 3 months of therapy, 5.4 ± 2.22 kg/m2 after 6 months, and 7.2 ± 3.07 kg/m2 after 12 months. The body weight reduction after 3, 6 and 12 months of treatment was 9.5%, 15.1%, and 19.7%, respectively. The body weight loss associated with sibutramine treatment was accompanied by a slight decrease in blood pressure and did not lead to any significant increases of the heart rate.

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